cancer,brain tumor,anti-cancer,vaccines,H5N1,flu,bacteria

BioJENC aims to research and develop new and/or improved products for better health. Our current focuses are: 1) cancer diagnostics and therapeutics, 2) viral vaccines, and 3) microbial detection devices.

Cancer diagnostics and therapeutics: analogs, inhibitors, vaccines

BioJENC has a special interest in developing anti-cancer agents against tumors in general, brain tumors in particular. We are particularly interested in astrocytomas including a relatively new entity named Rosetted Glioneuroma. We have targeted several areas of interest: epidermal growth factor receptor, tumor protein 53, heparan sulfate proteoglycans, fibroblast growth factors/receptors, telomerase, and others.

Tumor vaccines:

BioJENC has researched extensively to find links between virus and human cancer including brain tumors and has identified a viral protein with sequence motifs similar to a tumor-associated protein. Given that these two proteins also share a similar functionality, it is likely that these sequence motifs may play an essential role contributing to their common functionality. BioJENC has designed peptides for vaccine development targeting these sequence motifs.

Viral vaccines: BioJENC targets T-cell specific viral antigens for use as vaccine candidates against influenza (including seasonal flu viruses, human-adapted swine A/H1N1 virus, and bird flu virus/H5N1), HIV, and malaria. Our immediate goal in this area is to develop effective peptide vaccines against many strains of human pathogenic H5N1 virus including a potential pandemic strain, many strains of A/H1N1 virus, and HIV. A peptide vaccine that can induce an effective immune response to both A/H1N1 and H5N1 is under development.

Microbial detection devices:

BioJENC's sensitive differential culture medium can be used to isolate and culture Gram negative and Gram positive bacteria including but not limited to E. coli, Staphylococcus spp., Streptococcus spp., Pseudomonas spp., Enterobacter spp., Bacillus spp., and others. A rapid and sensitive reagent strip has also been developed to help differentiate nitrate-reducing bacteria and acid-producing bacteria (results within seconds).